Huw Dorkins

Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE

Nasim Mavaddat, Susan Peock, Debra Frost et al. · JNCI Journal of the National Cancer Institute · 2013 · 939 citations

Medicine, Gynecology, Oncology +17

Germline <i>BRCA</i> Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer

Elena Castro, Chee Goh, David Olmos et al. · Journal of Clinical Oncology · 2013 · 824 citations · Full text

Medicine, Oncology, Urology +17

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

Fergus J. Couch, Xianshu Wang, Lesley McGuffog et al. · PLoS Genetics · 2013 · 391 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies

Antonis C. Antoniou, Olga M. Sinilnikova, Jacques Simard et al. · The American Journal of Human Genetics · 2007 · 243 citations · Full text

Medicine, Genetics, Oncology +16

Population Testing for Cancer Predisposing BRCA1/BRCA2 Mutations in the Ashkenazi-Jewish Community: A Randomized Controlled Trial

Ranjit Manchanda, K Loggenberg, Saskia C. Sanderson et al. · JNCI Journal of the National Cancer Institute · 2014 · 186 citations · Full text

Medicine, Genetics, Molecular Genetics +17