David R. Manning

Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

Susanne M. Mumby, Richard Kahn, David R. Manning et al. · Proceedings of the National Academy of Sciences · 1986 · 381 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

Differential Coupling of the Sphingosine 1-Phosphate Receptors Edg-1, Edg-3, and H218/Edg-5 to the Gi, Gq, and G12 Families of Heterotrimeric G Proteins

Rolf T. Windh, Menq-Jer Lee, Timothy Hla et al. · Journal of Biological Chemistry · 1999 · 333 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The regulatory components of adenylate cyclase and transducin. A family of structurally homologous guanine nucleotide-binding proteins.

David R. Manning, Alfred G. Gilman · Journal of Biological Chemistry · 1983 · 302 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Activation of heterotrimeric G proteins by Smoothened

Natalia A. Riobo‐Del Galdo, Berangere Saucy, Cherisse DiLizio et al. · Proceedings of the National Academy of Sciences · 2006 · 240 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Loss of signaling through the G protein, G _z , results in abnormal platelet activation and altered responses to psychoactive drugs

Jing Yang, Jie Wu, M. Anna Kowalska et al. · Proceedings of the National Academy of Sciences · 2000 · 200 citations · Full text

Medicine, Molecular Biology, Pharmacology +17