Aaron C. Burns - Concepedia

Concepedia

Author

Aaron C. Burns

Stanford University ORCID

Also Known As

, Aaron Burns, Aaron C. Burns, Burns, Aaron C.

60

Publications

1.7K

Citations

16

H-Index

23

Concepts

All Affiliations

Stanford University Scripps Research Institute Mirati Therapeutics (United States)Pfizer (United States)University of Minnesota

AC

About

Aaron C. Burns is an author at Stanford University specializing in organic chemistry, natural sciences, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	5	5	310
2	Natural Sciences	5	5	311
3	Biochemistry	5	5	311
4	Biomolecular Engineering	4	4	119
5	Medicine	2	2	92

Aaron C. Burns

×

19

Publications

1.7K

Citations

16

H-Index

	Year	Citations
Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer Jay B. Fell, John P. Fischer, Brian R. Baer, Journal of Medicinal Chemistry	2020	559
C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase Jinghan Gui, Qianghui Zhou, Chung‐Mao Pan, Journal of the American Chemical Society Combinatorial ChemistryEngineeringZinc BisSimple ProtocolMolecular Biology	2014	191
Simple Sulfinate Synthesis Enables CH Trifluoromethylcyclopropanation Ryan Gianatassio, Shuhei Kawamura, Cecil L Eprile, Angewandte Chemie International Edition	2014	164
Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of <i>MTAP</i> -Deleted Cancers Christopher R. Smith, Ruth Aranda, Thomas P. Bobinski, Journal of Medicinal Chemistry	2022	139
Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer Joshua K. Sabari, Vamsidhar Velcheti, K. Shimizu, Clinical Cancer Research	2022	115
Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein–Protein Interaction John M. Ketcham, Jacob R. Haling, Shilpi Khare, Journal of Medicinal Chemistry	2022	87
Thionium Ion Initiated Medium-Sized Ring Formation: The Total Synthesis of Asteriscunolide D Barry M. Trost, Aaron C. Burns, Mark J. Bartlett, Journal of the American Chemical Society	2012	79
A Simple Litmus Test for Aldehyde Oxidase Metabolism of Heteroarenes Fionn O’Hara, Aaron C. Burns, Michael R. Collins, Journal of Medicinal Chemistry Bioorganic ChemistryMetabolomic ProfilingRedox BiologyPharmaceutical ChemistryOxidative Stress	2014	53
Palladium‐Catalyzed Asymmetric Allylic Alkylation of 3‐Aryloxindoles with Allylidene Dipivalate: A Useful Enol Pivalate Product Barry M. Trost, James T. Masters, Aaron C. Burns Angewandte Chemie International Edition Cross-coupling ReactionEngineeringAsymmetric Allylic AlkylationOrganic ChemistryCatalysis	2013	44
Simple Sulfinate Synthesis Enables CH Trifluoromethylcyclopropanation Ryan Gianatassio, Shuhei Kawamura, Cecil L Eprile, Angewandte Chemie	2014	44

Page 1