Concepedia

Aaron C. Burns

AC

19

Publications

1.7K

Citations

16

H-Index

2005

Active since

Affiliations

Stanford University(Current)

Scripps Research Institute

Mirati Therapeutics (United States)

Pfizer (United States)

University of Minnesota

Aaron C. Burns is an author at Stanford University specializing in organic chemistry, natural sciences, and pharmacology.

ORCID

Top concepts

Publications per year

2005–2024

19

Publications

19

Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer

Jay B. Fell, John P. Fischer, Brian R. Baer et al. · Journal of Medicinal Chemistry · 2020 · 559 citations · Full text

C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase

Jinghan Gui, Qianghui Zhou, Chung‐Mao Pan et al. · Journal of the American Chemical Society · 2014 · 191 citations · Full text

, , +18

Simple Sulfinate Synthesis Enables CH Trifluoromethylcyclopropanation

Ryan Gianatassio, Shuhei Kawamura, Cecil L Eprile et al. · Angewandte Chemie International Edition · 2014 · 164 citations

Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of <i>MTAP</i> -Deleted Cancers

Christopher R. Smith, Ruth Aranda, Thomas P. Bobinski et al. · Journal of Medicinal Chemistry · 2022 · 139 citations · Full text

Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer

Joshua K. Sabari, Vamsidhar Velcheti, K. Shimizu et al. · Clinical Cancer Research · 2022 · 115 citations · Full text

Rows per page

1–5 of 19