TL1A Is a TNF-like Ligand for DR3 and TR6/DcR3 and Functions as a T Cell Costimulator

Thi-Sau Migone, Jun Zhang, Xia Luo, +23

Immunity

Tnf-like LigandSignal TransductionT-regulatory CellImmunologyT Cell Costimulator +7

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

Marion Scharpfenecker, Maarten van Dinther, Zhen Liu, +5

Journal of Cell Science

Crystal Structure of BMP-9 and Functional Interactions with Pro-region and Receptors

Monica Brown, Qinghai Zhao, Kent A. Baker, +10

Journal of Biological Chemistry

Crystal StructureSclerostinMolecular BiologyCellular PhysiologyBone Morphogenic Protein +17

HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo

Laurie Pukac, Palanisamy Kanakaraj, Robin Humphreys, +19

British Journal of Cancer

An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis

Cecil Chen, Krzysztof Grzegorzewski, Steve Barash, +24

Nature Biotechnology

BioinformaticsMetabolic SyndromeFunctional GenomicsGeneticsGlucose Homeostasis +8

Heparin inhibits c-fos and c-myc mRNA expression in vascular smooth muscle cells.

Laurie Pukac, John J. Castellot, Thomas C. Wright, +2

Cell Regulation

ImmunologyCell GrowthCellular PhysiologyRat VsmcAngiogenesis +15

Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C-dependent pathway.

Thomas C. Wright, Laurie Pukac, John J. Castellot, +4

Proceedings of the National Academy of Sciences

ImmunologyCell ProliferationCell GrowthCellular PhysiologyTranscriptional Regulation +16

Platelet-Derived Growth Factor-BB, Insulin-like Growth Factor-I, and Phorbol Ester Activate Different Signaling Pathways for Stimulation of Vascular Smooth Muscle Cell Migration

Laurie Pukac, Jun Huangpu, Morris J. Karnovsky

Experimental Cell Research

ThrombosisSignal TransductionAngiogenesisBlood PlateletVascular Adaptation +8

Heparin suppresses specific second messenger pathways for protooncogene expression in rat vascular smooth muscle cells.

Laurie Pukac, Michael E. Ottlinger, M J Karnovsky

Journal of Biological Chemistry

Molecular RegulationCellular PhysiologyRat VsmcControl VsmcProtooncogene Expression +16

Heparin inhibits mitogen-activated protein kinase activation in intact rat vascular smooth muscle cells.

Michael E. Ottlinger, Laurie Pukac, Morris J. Karnovsky

Journal of Biological Chemistry

Cell CycleCellular PhysiologyAngiogenesisCell RegulationSignaling Pathway +18