Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

Yibin Liu, Paulina Siejka-Zielińska, Gergana Velikova, +7

Nature Biotechnology

Chemical MeasurementBiochemistryNatural SciencesChemical ImageBioanalysis +7

Transforming machine translation: a deep learning system reaches news translation quality comparable to human professionals

Martin Popel, Markéta Tomková, Jakub Tomek, +4

Nature Communications

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

Chiara Bardella, Osama Al‐Dalahmah, Daniel Krell, +21

Cancer Cell

Lineage PlasticityCell LineageDevelopmental BiologyMedicineStem Cell Research +6

Mutational signature distribution varies with DNA replication timing and strand asymmetry

Markéta Tomková, Jakub Tomek, Skirmantas Kriaučionis, +1

Genome biology

Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing

Henriette O’Geen, Markéta Tomková, Jacquelyn A Combs, +2

Nucleic Acids Research

DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine

Markéta Tomková, Michael McClellan, Skirmantas Kriaučionis, +1

DNA repair

ChromatinGenome InstabilityDna DamageNatural SciencesGenetics +12

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma

Thomas Carroll, Joseph A. Chadwick, Richard Owen, +74

Cancer Cell

Usefulness of N-Terminal Pro-Brain Natriuretic Peptide to Predict Mortality in Adults With Congenital Heart Disease

Jana Popelová, Karel Kotaška, Markéta Tomková, +1

The American Journal of Cardiology

Prognostic EvaluationHeart FailureCardiovascular EpidemiologyCardiovascular DiseaseCardiometabolic Risk +11

5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA

Markéta Tomková, Michael McClellan, Skirmantas Kriaučionis, +1

eLife

Human DNA polymerase ε is a source of C>T mutations at CpG dinucleotides

Markéta Tomková, Michael John McClellan, Gilles Crevel, +7

Nature Genetics

GeneticsMolecular BiologyMolecular GeneticsT MutationsPol ε +17