Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727

Qifang Zhang, Vidisha Raje, Vasily A. Yakovlev, +12

Journal of Biological Chemistry

Activation of murine pre-proglucagon–producing neurons reduces food intake and body weight

Ronald P. Gaykema, Brandon A. Newmyer, Matteo Ottolini, +11

Journal of Clinical Investigation

NutritionNeuroendocrinologyFood IntakeGlucose HomeostasisHypothalamic Circuits +20

Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production

Jeremy A. Meier, Moonjung Hyun, Marc Cantwell, +12

Science Signaling

Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity

Marta Derecka, Agnieszka Górnicka, Sergei B. Koralov, +21

Cell Metabolism

ObesityMetabolic SyndromeSignal TransductionSignaling PathwayReceptor Tyrosine Kinase +8

Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes

Garrett R. Mullins, Lifu Wang, Vidisha Raje, +8

Proceedings of the National Academy of Sciences

Metabolic RemodelingLipolysis Inhibit MtorInsulin SignalingMetabolic SyndromeNutrient Signalling +18

Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists

Salome Boroda, Maria Niccum, Vidisha Raje, +2

Biochemical Pharmacology

Molecular PharmacologyBiochemistryDgkα InhibitorsMedicineSerotonin Receptor Antagonists +8

Adipocyte lipolysis drives acute stress-induced insulin resistance

Vidisha Raje, Katelyn W. Ahern, Brittany A. Martínez, +11

Scientific Reports

The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes

Jennifer D. Sisler, Magdalena Morgan, Vidisha Raje, +10

PLoS ONE

Mitochondrial BiologyRedox BiologyOxidative StressInflammationMetabolic Syndrome +22

STAT3 suppresses Wnt/β-catenin signaling during the induction phase of primary Myf5+ brown adipogenesis

Marc Cantwell, Jared S. Farrar, Joseph Lownik, +8

Cytokine

Transcriptional RegulationSignal TransductionDevelopmental BiologySignaling PathwayMolecular Regulation +7

Kinase inactive Tyrosine kinase (Tyk2) Supports Differentiation of Brown fat Cells

Vidisha Raje, Marta Derecka, Marc Cantwell, +7

Endocrinology