The impact of antibiotic usage on the efficacy of chemoimmunotherapy is contingent on the source of tumor-reactive T cells

Michal Kuczma, Zhi‐Chun Ding, Tao Li, +7

Oncotarget

Antibiotic AdjuvantImmunologyImmunoeditingGut MicrobiotaBiological Therapy +21

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

Tsadik Habtetsion, Zhi‐Chun Ding, Wenhu Pi, +12

Cell Metabolism

Cancer MetabolismTumor MetabolismCancer ImmunosurveillanceMedicineApoptosis +12

Blockade of glutamine-dependent cell survival augments antitumor efficacy of CPI-613 in head and neck cancer

Liwei Lang, Fang Wang, Zhi‐Chun Ding, +8

Journal of Experimental & Clinical Cancer Research

Neck CancerOncologyGliomaMedicineImmune Checkpoint Inhibitor +7

Chemotherapy-induced myeloid suppressor cells and antitumor immunity: The Janus face of chemotherapy in immunomodulation

Zhi‐Chun Ding, David H. Munn, Gang Zhou

OncoImmunology

Tumor RecurrenceImmunologyJanus FacePathologyAntitumor Immunity +14

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Zhi‐Chun Ding, Tsadik Habtetsion, Yang Cao, +8

Scientific Reports

Structural prediction of the β‐domain of metallothionein‐3 by molecular dynamics simulation

Fengyun Ni, Bin Cai, Zhi‐Chun Ding, +5

Proteins Structure Function and Bioinformatics

Mutation at Glu23 eliminates the neuron growth inhibitory activity of human metallothionein-3

Zhi‐Chun Ding, Xin-Chen Teng, Bin Cai, +8

Biochemical and Biophysical Research Communications

Developmental BiologyMolecular NeuroscienceGrowth HormoneHuman GrowthHuman Metallothionein-3 +5

The molecular mechanism for human metallothionein-3 to protect against the neuronal cytotoxicity of Aβ1–42 with Cu ions

Ying Luo, Yuxia Xu, Qingui Bao, +4

JBIC Journal of Biological Inorganic Chemistry

Cu IonsMolecular PharmacologyMolecular NeuroscienceBiochemistryMedicine +11

Effect of α-domain substitution on the structure, property and function of human neuronal growth inhibitory factor

Zhi‐Chun Ding, Qi Zheng, Bin Cai, +8

JBIC Journal of Biological Inorganic Chemistry

Synaptic PlasticityMolecular PhysiologyDevelopmental BiologyMolecular NeuroscienceHuman Growth +10

Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy

Nada S. Aboelella, Caitlin Brandle, Ogacheko Okoko, +10

Journal for ImmunoTherapy of Cancer