Synthesis and in vitro evaluation of potential anticancer activity of mono- and bis-1,2,3-triazole derivatives of bis-alkynes

Hichem Elamari, Riadh Slimi, Guy G. Chabot, +3

European Journal of Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)MedicineOrganic ChemistryPotential Anticancer Activity +8

Synthesis and biological evaluation of novel ferrocenyl curcuminoid derivatives

Anusch Arezki, Guy G. Chabot, Lionel Quentin, +3

MedChemComm

NanomedicineMedicinal ChemistryDerivative (Chemistry)BiochemistryNatural Sciences +11

Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae)

Hoang Linh, Guy G. Chabot, Philippe Grellier, +8

European Journal of Medicinal Chemistry

BiologyHerbal MedicineAnti-parasite ActivitiesPhytopharmacologyPhytochemical +3

In vitro and in vivo biological evaluation of new 4,5-disubstituted 1,2,3-triazoles as cis-constrained analogs of combretastatin A4

Núria Mur Blanch, Guy G. Chabot, Lionel Quentin, +3

European Journal of Medicinal Chemistry

Medicinal ChemistryMedicineVivo Biological EvaluationCis-constrained AnalogsCombretastatin A4 +3

Synthesis of cytotoxic ferrocenyl flavones via a ferricenium-mediated 1,6-oxidative cyclization

Jean‐Philippe Monserrat, Guy G. Chabot, Louis Hamon, +4

Chemical Communications

Ferrocenyl chalcone difluoridoborates inhibit HIV-1 integrase and display low activity towards cancer and endothelial cells

Jean‐Philippe Monserrat, Rasha I. Al-Safi, Keshri Nath Tiwari, +6

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryAntiviral CompoundEndothelial CellsMedicineImmunology +9

Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells

Jean‐Philippe Monserrat, Keshri Nath Tiwari, Lionel Quentin, +5

Journal of Organometallic Chemistry

InflammationEndothelial CellsMedicineMelanomaCell Death +7

Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4

Nancy Ty, Renée Pontikis, Guy G. Chabot, +4

Bioorganic & Medicinal Chemistry

Natural SciencesMedicineDiversity-oriented SynthesisPure Cyclopropyl AnaloguesMolecular Biology +8

Domino approach to 2-aroyltrimethoxyindoles as novel heterocyclic combretastatin A4 analogues

Martin Arthuis, Renée Pontikis, Guy G. Chabot, +3

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryHeterocyclicNatural Sciences +6

Structure–activity relationships of indole compounds derived from combretastatin A4: Synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents

Nancy Ty, Grégory Dupeyre, Guy G. Chabot, +7

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryNatural SciencesMedicineIndole Compounds +6