Gaoyuan Zhu

Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity

Junyu Xu, Hongmei Li, Xinren Wang et al. · European Journal of Medicinal Chemistry · 2020 · 41 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +8

Design, synthesis and evaluation of derivatives based on pyrimidine scaffold as potent Pan-Raf inhibitors to overcome resistance

Lu Wang, Qing Zhang, Gaoyuan Zhu et al. · European Journal of Medicinal Chemistry · 2017 · 22 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Derivatives +11

Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance

Lu Wang, Gaoyuan Zhu, Qing Zhang et al. · Organic & Biomolecular Chemistry · 2017 · 17 citations

DMAP-promoted in situ activation of bromoacetic acid as a 2-carbon synthon for facile synthesis of pyridines and fused pyridin-2-ones

Lu Wang, Gaoyuan Zhu, Weifang Tang et al. · Tetrahedron · 2016 · 11 citations

Engineering, Biochemistry, Natural Sciences +8

Discovery of potent Pan-Raf inhibitors with increased solubility to overcome drug resistance

Lu Wang, Yanmin Zhang, Qing Zhang et al. · European Journal of Medicinal Chemistry · 2018 · 11 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +11