Rosemary O’Brien

The Bcl-2 Homology Domain 3 Mimetic ABT-737 Targets the Apoptotic Machinery in Acute Lymphoblastic Leukemia Resulting in Synergistic in Vitro and in Vivo Interactions with Established Drugs

Laura High, Barbara Szymanska, Urszula Wilczynska-Kalak et al. · Molecular Pharmacology · 2009 · 118 citations

<i>MYC</i> -Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Rosemary O’Brien, Sieu L. Tran, Michelle F. Maritz et al. · Cancer Research · 2016 · 53 citations

FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation

Alena Malyukova, Scott D. Brown, Rachael A. Papa et al. · Leukemia · 2012 · 48 citations · Full text

Hematological Malignancy, Lymphoid Neoplasia, Autoimmune Disease +12

<i>DKC1</i> is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts

Laura Richards, Ashu Kumari, Kathy Knezevic et al. · Haematologica · 2019 · 26 citations · Full text

Up-regulation of Survivin during Immortalization of Human Myofibroblasts Is Linked to Repression of Tumor Suppressor p16INK4a Protein and Confers Resistance to Oxidative Stress

Chin-Yi Kan, Carlotta Petti, Lauryn S. Bracken et al. · Journal of Biological Chemistry · 2013 · 10 citations · Full text