THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer

Mayuki Omatsu, Yuki Nakanishi, Kosuke Iwane, +40

Nature Communications

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine

Yu Muta, Yoshihisa Fujita, Kenta Sumiyama, +7

Nature Communications

Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer

Anxo Martínez-Ordóñez, Ángeles Durán, Marc Ruíz-Martínez, +20

Cancer Cell

Tumor BiologyOncologyMedicineMesenchymal Colorectal CancerPathology +10

Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis

Tomonori Masuda, Akihisa Fukuda, Go Yamakawa, +20

Journal of Clinical Investigation

Pancreatic Reck InactivationTumor BiologyHuman PdacPancreatic CancerMedicine +10

First jejunal vein oriented mesenteric excision for pancreatoduodenectomy

Masafumi Nakamura, Hiroshi Nakashima, Kosuke Tsutsumi, +7

Journal of Gastroenterology

GastroenterologyVascular SurgeryPancreatic SurgerySurgeryFirst Jejunal Vein +1

Mouse model of colorectal cancer: Orthotopic co-implantation of tumor and stroma cells in cecum and rectum

Hiroaki Kasashima, Ángeles Durán, Tania Cid-Diaz, +5

STAR Protocols

Loss of Arid1a and Pten in Pancreatic Ductal Cells Induces Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway

Yuichi Fukunaga, Akihisa Fukuda, Mayuki Omatsu, +17

Gastroenterology

Signal TransductionSignaling PathwayPancreatic CancerCell SignalingPathology +5

Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis

Yu Muta, Juan F. Linares, Anxo Martínez-Ordóñez, +23

Nature Communications

Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway

Osamu Araki, Motoyuki Tsuda, Mayuki Omatsu, +19

Oncogene

Descending Necrotizing Mediastinitis Treated with Tooth Extractions following Mediastinal and Cervical Drainage

Minoru Fukuchi, Okihide Suzuki, Daisuke Nasu, +8

Case Reports in Gastroenterology

Necrotizing Mediastinitis TreatedTooth ExtractionResidual Cervical AbscessCervical FasciaTooth Extractions +11