Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter

Theodora Agalioti, Stavros Lomvardas, Bhavin S. Parekh, +3

Cell

GeneticsEpigeneticsIfn-β PromoterTranscriptional RegulationTranscription Factors +14

Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

Jer-Yuan Hsu, Suzanne Crawley, Michael Chen, +31

Nature

Metabolic SyndromeEnergy HomeostasisMolecular PhysiologyNeurophysiologyBrainstem-restricted Receptor +10

Structure of IRF-1 with bound DNA reveals determinants of interferon regulation

Carlos Escalante, Junming Yie, Dimitris Thanos, +1

Nature

Transcriptional RegulationSystems BiologyMolecular RegulationInterferon RegulationNatural Sciences +7

Acetylation of HMG I(Y) by CBP Turns off IFNβ Expression by Disrupting the Enhanceosome

Nikhil Munshi, Menie Merika, Junming Yie, +3

Molecular Cell

Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms

Elisabetta Mueller, Stavit Drori, Anita Aiyer, +8

Journal of Biological Chemistry

Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models

Elizabeth A. Killion, Jinghong Wang, Junming Yie, +22

Science Translational Medicine

Glp-1r AgonistsAnti-obesity EffectsImmunologyAnti-gipr AntibodiesPharmacotherapy +18

Cell-Type-Specific Regulation of the Human Tumor Necrosis Factor Alpha Gene in B Cells and T Cells by NFATp and ATF-2/JUN

Eunice Y. Tsai, Junming Yie, Dimitris Thanos, +1

Molecular and Cellular Biology

T-regulatory CellImmunologyImmune RegulationPathologyCell Death +19

The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome

Junming Yie

The EMBO Journal

Ifn-beta EnhanceosomeChromatinProtein FunctionProtein AssemblyNatural Sciences +5

Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes

Randy Hecht, Yuesheng Li, Jeonghoon Sun, +18

PLoS ONE

Human GrowthPeptide ScienceBiomedical EngineeringNative Fgf21Rationale-based Engineering +22

FGF21 N‐ and C‐termini play different roles in receptor interaction and activation

Junming Yie, Randy Hecht, Jennifer Patel, +16

FEBS Letters

Cellular PhysiologyMolecular PharmacologySignaling PathwayCell RegulationReceptor Tyrosine Kinase +16