Addition of radium-223 to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases (ERA 223): a randomised, double-blind, placebo-controlled, phase 3 trial

Matthew R. Smith, Chris Parker, Fred Saad, +21

The Lancet Oncology

Era 223UrologyMedicineClinical TrialsPharmacotherapy +6

Sequence Identification and Characterization of Human Carnosinase and a Closely Related Non-specific Dipeptidase

Michael Teufel, Vladimı́r Saudek, Jean-Pierre Ledig, +13

Journal of Biological Chemistry

Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trial

Josep Tabernero, Heinz‐Josef Lenz, Salvatore Siena, +16

The Lancet Oncology

Biomarker (Medicine)Prognostic BiomarkersOncologyProtein BiomarkersMedicine +9

Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA.

Utz Fischer, Sylvie C. Meyer, Michael Teufel, +3

The EMBO Journal

Transcriptional RegulationNuclear ExportViral ReplicationHiv-1 RevNatural Sciences +13

Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma

Michael Teufel, Henrik Seidel, Karl Köchert, +4

Gastroenterology

Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with <i>RAS</i>-Mutated Hepatocellular Carcinoma

Ho Yeong Lim, Philippe Merle, Karl Weiss, +24

Clinical Cancer Research

Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer

Jean‐Luc Van Laethem, Hanno Riess, Jacek Jassem, +22

Targeted Oncology

Pancreatic CancerGastrointestinal OncologyPhase I/ii StudyMedicinePharmacology +8

Antitumor effects of regorafenib and sorafenib in preclinical models of hepatocellular carcinoma

Maria Kissel, Sandra Berndt, Lukas Fiebig, +7

Oncotarget

Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle

Utz Fischer, Victoria W. Pollard, Reinhard Lührmann, +4

Nucleic Acids Research

Viral ReplicationXenopus Laevis OocytesGeneticsMolecular BiologyRev Response Element +16

Solution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamics

Christian Sich, Sabina Improta, David J. Cowley, +4

European Journal of Biochemistry