S.-H. Li

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

Michael A. Gray, Dyna Shirasaki, Carlos Cepeda et al. · Journal of Neuroscience · 2008 · 605 citations · Full text

Genetics, Selective Neuropathogenesis, Transgenic Mouse Model +16

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

S.-H. Li, Gabriele Schilling, W. Scott Young et al. · Neuron · 1993 · 342 citations

Genetic Disorder, Natural Sciences, Disease Gene +8

Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis

S.-H. Li · Human Molecular Genetics · 2000 · 119 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Signaling Pathway +14

Huntingtin-associated protein-1 is a modifier of the age-at-onset of Huntington's disease

S Metzger, Huu Phuc Nguyen, Austin Cape et al. · Human Molecular Genetics · 2008 · 91 citations · Full text

Amino Acid 441, Functional Assays, Huntingtin-associated Protein-1 +12