Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Filipe Cabreiro, Catherine Au, Kit‐Yi Leung, +7

Cell

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

Sally J. Leevers, David Weinkove, Lindsay K. MacDougall, +2

The EMBO Journal

Signaling PathwayCell RegulationMedicineCell BiologyCell Signaling +1

Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans

Timothy M. Bass, David Weinkove, Koen Houthoofd, +2

Mechanisms of Ageing and Development

BiologyDrosophila MelanogasterLifespan ExtensionLongevityGenetics +7

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children

Chenhong Zhang, Aihua Yin, Hongde Li, +37

EBioMedicine

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class IA phosphoinositide 3-kinase and its adaptor

David Weinkove, Thomas P. Neufeld, Thomas Twardzik, +2

Current Biology

Cell LineageDevelopmental BiologyOrgan SizeMedicineCell Number +7

Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm

David Weinkove, Jonathan R. Halstead, David Gems, +1

BMC Biology

Excessive folate synthesis limits lifespan in the C. elegans: E. coliaging model

Bhupinder Virk, Gonçalo dos Santos Correia, David P. Dixon, +9

BMC Biology

Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy

Mark R. Lundquist, Marcus D. Goncalves, Ryan M. Loughran, +20

Molecular Cell

Cell AutophagyMitophagySignal TransductionAutophagyLipophagy +4

Folate Acts in E. coli to Accelerate C. elegans Aging Independently of Bacterial Biosynthesis

Bhupinder Virk, Jie Jia, Claire Maynard, +8

Cell Reports

BiologyLifespan ExtensionWorm LifespanBiosynthesisE. Coli +12

A Casein Kinase 1 and PAR Proteins Regulate Asymmetry of a PIP2 Synthesis Enzyme for Asymmetric Spindle Positioning

Costanza Panbianco, David Weinkove, Esther Zanin, +4

Developmental Cell