cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Carolina Uggenti, Alice Lepelley, Marine Depp, +53

Nature Genetics

ChromatinInborn ErrorsChromatin RemodelingGeneticsCgas-mediated Induction +8

In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord

Marco Morsch, Rowan A. W. Radford, Albert Lee, +5

Frontiers in Cellular Neuroscience

Vivo CharacterizationNeuroanatomyMicroglial EngulfmentMedicineZebrafish Spinal Cord +11

Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

Adam J. Svahn, Emily K. Don, Andrew P. Badrock, +5

Acta Neuropathologica

A Tol2 Gateway-Compatible Toolbox for the Study of the Nervous System and Neurodegenerative Disease

Emily K. Don, Isabel Formella, Andrew P. Badrock, +10

Zebrafish

EngineeringDisease ProgressionNeurochemical BiomarkersTol2 Gateway-compatible ToolboxExperimental Neuropathology +15

Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis

Yeliz Boglev, Andrew P. Badrock, Andrew J. Trotter, +20

PLoS Genetics

Zebrafish IL-4–like Cytokines and IL-10 Suppress Inflammation but Only IL-10 Is Essential for Gill Homeostasis

Federica Bottiglione, Christopher Dee, Robert Lea, +7

The Journal of Immunology

Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached

Daniel J. Wilcock, Andrew P. Badrock, Chun Wai Wong, +18

Cell Reports

Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish

Fiona Henderson, Hannah Johnston, Andrew P. Badrock, +19

Cancer Research

Mutant Human FUS Is Ubiquitously Mislocalized and Generates Persistent Stress Granules in Primary Cultured Transgenic Zebrafish Cells

Jamie Rae Acosta, Claire Goldsbury, Claire Winnick, +9

PLoS ONE

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisDevelopmental BiologyCell LineageMotor Neurons +12

RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation

Berta Casar, Andrew P. Badrock, Iñaki Jiménez, +10

Nature Communications