A Physiologically-Based Pharmacokinetic Model to Predict Human Fetal Exposure for a Drug Metabolized by Several CYP450 Pathways

Maïlys De Sousa Mendes, Gabrielle Lui, Yi Zheng, +8

Clinical Pharmacokinetics

Several Cyp450 PathwaysPharmacokinetic ModelingDrug MetabolizedPharmacological StudyPhysiology +9

Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children with Normal and Augmented Renal Clearance

Agathe Béranger, Sihem Benaboud, Florence Moulin, +9

Clinical Pharmacokinetics

Critical Care MedicinePiperacillin Population PharmacokineticsAugmented Renal ClearanceMedicineCritically Ill Children +9

Pharmacokinetics and pharmacodynamics of tacrolimus in liver transplant recipients: inside the white blood cells

Benoı̂t Blanchet, Marianne Latournerie, Marie Antignac, +12

Clinical Biochemistry

White Blood CellsTransplantationHepatologyLiver Transplant RecipientsImmunosuppressive Therapy +7

Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction

Bo-Hao Tang, Zheng Guan, Karel Allegaert, +31

Clinical Pharmacokinetics

Drug SafetyPharmacokinetic ModelingMachine Learning ApproachesMedicinePredictive Analytics +7

Population pharmacokinetics of meropenem in critically ill children with different renal functions

M. Rapp, Frantz Foissac, Agathe Béranger, +11

European Journal of Clinical Pharmacology

Ill ChildrenRenal FunctionMedicineKidney FailurePediatrics +8

Population Pharmacokinetics and Dosing Optimization of Amoxicillin in Neonates and Young Infants

Bo‐Hao Tang, Yue‐E Wu, Chen Kou, +10

Antimicrobial Agents and Chemotherapy

NeonatologyPharmacokinetic ModelingAntibioticsYoung InfantsEarly-onset Sepsis +12

Simultaneous quantification of levofloxacin, pefloxacin, ciprofloxacin and moxifloxacin in microvolumes of human plasma using high‐performance liquid chromatography with ultraviolet detection

Yi Zheng, Ziqing Wang, Gabrielle Lui, +5

Biomedical Chromatography

Maternal Betamethasone for Prevention of Respiratory Distress Syndrome in Neonates: Population Pharmacokinetic and Pharmacodynamic Approach

Frantz Foissac, Yi Zheng, Déborah Hirt, +10

Clinical Pharmacology & Therapeutics

NeonatologyMaternal BetamethasoneRespiratory Distress Syndrome (Pulmonary Critical Care)Pediatric Lung DiseaseHigh-risk Pregnancy +15

HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-β-d-glucuronide in human plasma

Yi Zheng, Radia Aboura, Sana Boujaafar, +7

Journal of Pharmaceutical and Biomedical Analysis

MedicineBioanalysisMass SpectrometryAntiviral Drug DevelopmentAntiviral Therapy +9

Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates

Bo‐Hao Tang, Jinyuan Zhang, Karel Allegaert, +21

Clinical Pharmacokinetics

Therapeutic Drug MonitoringDosage IndividualizationMachine LearningAntibioticsPediatrics +4