Stem cell competition orchestrates skin homeostasis and ageing

Nan Liu, Hiroyuki Matsumura, Tomoki Kato, +10

Nature

Skin DevelopmentDevelopmental BiologyMedicineCutaneous BiologyAdult Stem Cell +4

Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function

Ryo Iwamoto, Satoru Yamazaki, Masanori Asakura, +12

Proceedings of the National Academy of Sciences

Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing

Yuji Shirakata, Rina Kimura, Daisuke Nanba, +8

Journal of Cell Science

Skin DevelopmentCutaneous BiologyKeratinocyte MigrationSkin Wound HealingPredominant Growth Factor +10

Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF

Daisuke Nanba, Akiko Mammoto, Koji Hashimoto, +1

The Journal of Cell Biology

PACSIN3 Binds ADAM12/Meltrin α and Up-regulates Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth Factor

Seiji Mori, Motonari Tanaka, Daisuke Nanba, +4

Journal of Biological Chemistry

ADAM Binding Protein Eve-1 Is Required for Ectodomain Shedding of Epidermal Growth Factor Receptor Ligands

Motonari Tanaka, Daisuke Nanba, Seiji Mori, +5

Journal of Biological Chemistry

Developmental BiologySignaling PathwaySkeletal MuscleHuman GrowthMouse Sh3d19 +10

EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis

Daisuke Nanba, Fujio Toki, Kyosuke Asakawa, +6

The Journal of Cell Biology

Skin Regenerative CapacityCell ProliferationDermatologyCol17a1 ProteolysisSkin Regeneration +14

Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression

Ken Shiraishi, Kenshi Yamasaki, Daisuke Nanba, +5

Oncogene

Transcriptional RegulationCell RegulationMedicineMixed-phenotype Acute LeukemiaCell Proliferation +7

PLZF regulates Pbx1 transcription and Pbx1–HoxC8 complex leads to androgen-independent prostate cancer proliferation

Tadahiko Kikugawa, Yumi Kinugasa, Ken Shiraishi, +5

The Prostate

Actin filament dynamics impacts keratinocyte stem cell maintenance

Daisuke Nanba, Fujio Toki, Natsuki Matsushita, +3

EMBO Molecular Medicine

Developmental BiologyMedicineStem Cell ResearchCell MotilityCell Biomechanics +6