Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

Roxane Siméone, Alexandre Bobard, Juliane Lippmann, +4

PLoS Pathogens

Microbial PathogensTuberculosis PreventionImmunologyImmune RegulationAntigen Processing +19

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

Philip Supply, Michaël Marceau, Sophie Mangenot, +35

Nature Genetics

p62 and NDP52 Proteins Target Intracytosolic Shigella and Listeria to Different Autophagy Pathways

Serge Mostowy, Vanessa Sancho‐Shimizu, Mélanie Hamon, +4

Journal of Biological Chemistry

Cell AutophagySelective AutophagyVirulence FactorDifferent Autophagy PathwaysPathogenesis +10

ESX-1 dependent impairment of autophagic flux by<i><i>Mycobacterium tuberculosis</i></i>in human dendritic cells

Alessandra Romagnoli, Marilena P. Etna, Elena Giacomini, +12

Autophagy

Adaptive Immune SystemAutophagic FluxImmunologyImmune RegulationImmune System +16

ESX-1 and phthiocerol dimycocerosates of<i>Mycobacterium tuberculosis</i>act in concert to cause phagosomal rupture and host cell apoptosis

Jacques Augenstreich, Ainhoa Arbués, Roxane Siméone, +9

Cellular Microbiology

Pulmonary TuberculosisMicrobial PathogensOuter MembraneVirulence FactorPathogenesis +13

Characterization of<i>Mycobacterium orygis</i>as<i>M. tuberculosis</i>Complex Subspecies

Jakko van Ingen, Zeaur Rahim, A. Mulder, +4

Emerging infectious diseases

BiologyPulmonary TuberculosisOryx BacilliTuberculosis PreventionBacteriology +7

Disruption of the ESX‐5 system of <i>Mycobacterium tuberculosis</i> causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

Daria Bottai, Mariagrazia Di Luca, Laleh Majlessi, +10

Molecular Microbiology

Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

Roxane Siméone, Fadel Sayes, Ok‐Ryul Song, +4

PLoS Pathogens

The distinct fate of smooth and rough<i>Mycobacterium abscessus</i>variants inside macrophages

Anne‐Laure Roux, Albertus Viljoen, Aïcha Bah, +13

Open Biology

Strong Immunogenicity and Cross-Reactivity of Mycobacterium tuberculosis ESX-5 Type VII Secretion -Encoded PE-PPE Proteins Predicts Vaccine Potential

Fadel Sayes, Lin Sun, Mariagrazia Di Luca, +8

Cell Host & Microbe

VaccinationPulmonary TuberculosisStrong ImmunogenicityVaccine DevelopmentMedicine +7