Hydrogen Sulfide Alleviates Liver Injury Through the S‐Sulfhydrated‐Kelch‐Like ECH‐Associated Protein 1/Nuclear Erythroid 2–Related Factor 2/Low‐Density Lipoprotein Receptor–Related Protein 1 Pathway

Shuang Zhao, Tianyu Song, Yue Gu, +12

Hepatology

A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity

Jiye Liu, Tianyu Song, Wenrong Zhou, +8

Leukemia

Genome-scale Crispr-cas9 ScreeningOff-target EffectMedicineImmunologyMyeloma Cells +9

S-nitrosylation of Hsp90 promotes cardiac hypertrophy in mice through GSK3β signaling

Shuang Zhao, Tianyu Song, Ziyu Wang, +6

Acta Pharmacologica Sinica

Cardiac MuscleCardiomyopathyMolecular PhysiologySignal TransductionCardiac Hypertrophy +7

Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis

Shuang Zhao, Xin Tang, Zian Miao, +17

Redox Biology

Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities

Liang Chang, Nancy Yoobin Jung, Adel Atari, +13

Nature Genetics

Drug TargetFunctional GenomicsEngineeringPredictive ToxicologySynthetic Biology +8

Identification of the sesquiterpene synthase AcTPS1 and high production of (–)-germacrene D in metabolically engineered Saccharomyces cerevisiae

Jiajia Liu, Chang Chen, Xiukun Wan, +7

Microbial Cell Factories

SLC44A2 regulates vascular smooth muscle cell phenotypic switching and aortic aneurysm

Tianyu Song, Shuang Zhao, Shanshan Luo, +20

Journal of Clinical Investigation

Vascular DiseaseAng Ii InfusionCellular PhysiologyTranscriptional RegulationAngiogenesis +19

CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver

Gaofeng Li, Tong Ji, Chen Jiang, +10

Cell Reports

Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma

Jiye Liu, Lijie Xing, Jiang Li, +19

Nature Communications

Hematological MalignancyCancer ImmunosurveillanceMedicineImmunologyImmunoediting +12

CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory

Tianyu Song, Shenghui Liang, Jiye Liu, +10

PLoS Genetics

Scffbxo7-mediated TurnoverSignal TransductionMolecular NeuroscienceSynaptic SignalingMolecular Physiology +11