Clément Hoguin

Targeted therapy in patients with PIK3CA-related overgrowth syndrome

Quitterie Venot, Thomas Blanc, Laureline Berteloot et al. · Nature · 2018 · 575 citations · Full text

Medicine, Molecular Medicine, Oncology +12

Alpelisib administration reduced lymphatic malformations in a mouse model and in patients

Florence Delestre, Quitterie Venot, Charles Bayard et al. · Science Translational Medicine · 2021 · 89 citations

Veterinary Medicine, Pathobiology, Rodent Medicine +3

Treatment of two infants with PIK3CA-related overgrowth spectrum by alpelisib

G Morin, C. Degrugillier-Chopinet, Marie Vincent et al. · The Journal of Experimental Medicine · 2022 · 70 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Sotorasib for Vascular Malformations Associated with <i>KRAS</i> G12C Mutation

Antoine Fraissenon, Charles Bayard, G Morin et al. · New England Journal of Medicine · 2024 · 34 citations

Medicine, Genetics, Molecular Genetics +11

PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption

Sophia Ladraa, Lola Zerbib, Charles Bayard et al. · Science Advances · 2022 · 31 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17