Laurent Miccoli

Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore

L Ravagnan, Isabel Marzo, Paola Costantini et al. · Oncogene · 1999 · 211 citations

Mitophagy, Bcl-2-inhibited Effect, Mitochondrial Function +11

High glycolysis in gliomas despite low hexokinase transcription and activity correlated to chromosome 10 loss

Stéphane Oudard, Francisco Arvelo, Laurent Miccoli et al. · British Journal of Cancer · 1996 · 123 citations · Full text

Neuro-oncology, Glioma, Malignant Disease +9

Gliomas are driven by glycolysis: putative roles of hexokinase, oxidative phosphorylation and mitochondrial ultrastructure.

Stéphane Oudard, Eric Boitier, Laurent Miccoli et al. · PubMed · 1997 · 97 citations

Total Hk, Mitophagy, Pathology +22

Light-induced photoactivation of hypericin affects the energy metabolism of human glioma cells by inhibiting hexokinase bound to mitochondria.

Laurent Miccoli, Arnaud Beurdeley‐Thomas, Gonzague de Pinieux et al. · PubMed · 1998 · 89 citations

Hexokinase Bound, Photobiology, Optogenetics +23

Methionine depletion enhances the antitumoral efficacy of cytotoxic agents in drug-resistant human tumor xenografts.

Florence Poirson–Bichat, R A Gonçalves, Laurent Miccoli et al. · PubMed · 2000 · 79 citations

Tumor Biology, Cytotoxic Agents, Methionine-free Diet +15