Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis

Nozomi Takahashi, Miyuki Harada, Yasushi Hirota, +13

Scientific Reports

Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS

Jerilee Mariam Khong Azhary, Miyuki Harada, Nozomi Takahashi, +9

Endocrinology

ApoptosisImmunologyCell DeathGynecologyPolycystic Ovary Syndrome +17

Androgens Increase Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

Jerilee Mariam Khong Azhary, Miyuki Harada, Chisato Kunitomi, +11

Endocrinology

Evidence of the activation of unfolded protein response in granulosa and cumulus cells during follicular growth and maturation

Miyuki Harada, Emi Nose, Nozomi Takahashi, +6

Gynecological Endocrinology

OocyteCell GrowthCellular PhysiologyEmbryologyCumulus Cells +15

Activation of endoplasmic reticulum stress mediates oxidative stress–induced apoptosis of granulosa cells in ovaries affected by endometrioma

Chisato Kunitomi, Miyuki Harada, Nozomi Takahashi, +11

Molecular Human Reproduction

Redox SignalingGranulosa CellsFemale InfertilityStress–induced ApoptosisUterine Receptivity +13

Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome

Mutsumi Kobayashi, Osamu Yoshino, Akitoshi Nakashima, +11

Molecular and Cellular Endocrinology

Cell AutophagyMitophagySignal TransductionDevelopmental BiologyPai-1 Expression +9

Accumulation of advanced glycation end products in follicles is associated with poor oocyte developmental competence

Nozomi Takahashi, Miyuki Harada, Jerilee Mariam Khong Azhary, +10

Molecular Human Reproduction

Mitochondrial density contributes to the immune response of macrophages to lipopolysaccharide via the MAPK pathway

Emiko Kasahara, Atsuo Sekiyama, Mika Hori, +7

FEBS Letters

A potential role of endoplasmic reticulum stress in development of ovarian hyperstimulation syndrome

Nozomi Takahashi, Miyuki Harada, Yasushi Hirota, +10

Molecular and Cellular Endocrinology

InfertilityDevelopmental BiologyFemale InfertilityOogenesisStress +10

Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome

Chisato Kunitomi, Miyuki Harada, Akari Kusamoto, +11

Molecular Human Reproduction

ImmunologyGynecologyPolycystic Ovary SyndromeEr StressFemale Reproductive System +21