Giulia Lestini

First‐in‐human safety, tolerability, and pharmacokinetic results of DFV890, an oral low‐molecular‐weight NLRP3 inhibitor

Ewa Gatlik, Beata Mehes, Emilie Voltz et al. · Clinical and Translational Science · 2024 · 45 citations · Full text

PFIM 4.0, an extended R program for design evaluation and optimization in nonlinear mixed-effect models

Cyrielle Dumont, Giulia Lestini, Hervé Le Nagard et al. · Computer Methods and Programs in Biomedicine · 2018 · 40 citations · Full text

Engineering, Pfim 4.0, Metamodeling Technique +7

Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development

MJ Swat, Stuart Moodie, NR Kristensen et al. · CPT Pharmacometrics & Systems Pharmacology · 2015 · 38 citations · Full text

Model Exchange, Translational Medicine, Pharmacometrics Markup Language +13

Model Description Language (MDL): A Standard for Modeling and Simulation

Michael K. Smith, Stuart Moodie, Roberto Bizzotto et al. · CPT Pharmacometrics & Systems Pharmacology · 2017 · 16 citations · Full text

Influence of the Size of Cohorts in Adaptive Design for Nonlinear Mixed Effects Models: An Evaluation by Simulation for a Pharmacokinetic and Pharmacodynamic Model for a Biomarker in Oncology

Giulia Lestini, Cyrielle Dumont, France Mentré · Pharmaceutical Research · 2015 · 14 citations · Full text

Oncology, Pharmacokinetic Modeling, Engineering +10