Samuel Outteridge

Platelet P2Y ₁₂ Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model

Mark R. Thomas, Samuel Outteridge, Ramzi Ajjan et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2015 · 129 citations · Full text

Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (<scp>MATE</scp>) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine

Robert Elsby, Stephen Chidlaw, Samuel Outteridge et al. · Pharmacology Research & Perspectives · 2017 · 46 citations · Full text

Mechanistic In Vitro Studies Indicate that the Clinical Drug-Drug Interaction between Telithromycin and Simvastatin Acid Is Driven by Time-Dependent Inhibition of CYP3A4 with Minimal Effect on OATP1B1

Robert Elsby, Victoria Hare, Hannah Neal et al. · Drug Metabolism and Disposition · 2018 · 17 citations · Full text