Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts

Steven Dooley, Bert Delvoux, Birgit Lahme, +2

Hepatology

Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes

O Gressner, Birgit Lahme, Ilhan Demirci, +2

Journal of Hepatology

FibrosisDifferential EffectsHepatologyHepatic Stellate CellsMedicine +13

Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor expression in hepatocytes via PPARγ and SMAD2/3-dependent pathways

O Gressner, Birgit Lahme, Katharina Rehbein, +3

Journal of Hepatology

Molecular PharmacologyPharmacological ApplicationHealth SciencesSmad2/3-dependent PathwaysMedicine +8

Transformation-dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble fas ligand

Wenrong Gong, Adalı́ Pecci, Birgit Lahme, +2

Hepatology

Liver FibrosisHepatic Stellate CellsApoptosisImmunologyCell Death +25

Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells

Hans Sprenger, Andreas M. Kaufmann, Holger Garn, +3

Gastroenterology

InflammationNeutrophil-attracting ChemokinesGranulocyteCell SignalingCell Trafficking +10

TGF-β-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes

Axel M. Gressner, Birgit Lahme, Hans Georg Mannherz, +1

Journal of Hepatology

HepatologyMedicineLiver PhysiologyApoptosisCell Death +8

Elevation of Nε-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosis

Eray Yagmur, Frank Tacke, Birgit Lahme, +4

Clinical Biochemistry

HepatologyBiochemistryMedicineLiver PhysiologyChronic Liver Disease +7

Connective Tissue Growth Factor in Serum as a New Candidate Test for Assessment of Hepatic Fibrosis

Axel M. Gressner, Eray Yagmur, Birgit Lahme, +2

Clinical Chemistry

Identification and Partial Characterization of A Hepatocyte–Derived Factor Promoting Proliferation of Cultured Fat–Storing Cells (Parasinusoidal Lipocytes)

Axel M. Gressner, Sina Lotfi, Gabriele Gressner, +1

Hepatology

Induction of rat liver parenchymal cell apoptosis by hepatic myofibroblasts via transforming growth factor β

Axel M. Gressner, Bernhard Polzar, Birgit Lahme, +1

Hepatology