Joshua P. Taygerly

AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies

Sean Caenepeel, Sean P. Brown, Brian Belmontes et al. · Cancer Discovery · 2018 · 408 citations · Full text

Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction

K.R. Simonetta, Joshua P. Taygerly, Kathleen Boyle et al. · Nature Communications · 2019 · 196 citations · Full text

Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

Yan Lou, Xiaochun Han, A. Kuglstatter et al. · Journal of Medicinal Chemistry · 2014 · 106 citations

Pharmaceutical Science, Tyrosine Kinase, Immunology +18

A convenient guide to help select replacement solvents for dichloromethane in chromatography

Joshua P. Taygerly, Larry Miller, Alicia Yee et al. · Green Chemistry · 2012 · 88 citations

Discovery of INT131: A selective PPARγ modulator that enhances insulin sensitivity

Joshua P. Taygerly, Lawrence R. McGee, Steven M. Rubenstein et al. · Bioorganic & Medicinal Chemistry · 2012 · 42 citations · Full text

Molecular Pharmacology, Selective Pparγ Modulator, Insulin Sensitivity +11