David Spetzler

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Dung T. Le, Jennifer N. Durham, Kellie N. Smith et al. · Science · 2017 · 6.4K citations

Solid Tumors, Pd-1 Blockade, Immunology +16

Microsatellite instability status determined by next‐generation sequencing and compared with <scp>PD</scp>‐L1 and tumor mutational burden in 11,348 patients

Ari M. Vanderwalde, David Spetzler, Nianqing Xiao et al. · Cancer Medicine · 2018 · 458 citations · Full text

Genetics, Genetic Epidemiology, Immunology +19

Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy

Tiffany R. Hodges, Martina Ott, Joanne Xiu et al. · Neuro-Oncology · 2017 · 419 citations · Full text

Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies

Sarah T. Garber, Yuuri Hashimoto, Shiao-Pei Weathers et al. · Neuro-Oncology · 2016 · 138 citations · Full text

Microsecond Time Scale Rotation Measurements of Single F₁-ATPase Molecules

David Spetzler, Justin York, Douglas Daniel et al. · Biochemistry · 2006 · 114 citations · Full text