Kyra J. Cowan

Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor

Rong Deng, Daniela Bumbaca, Cinthia V. Pastuskovas et al. · mAbs · 2016 · 196 citations · Full text

Radioactivity Ratio, Immunology, Immunotherapeutics +17

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

Yanan Zheng, Devin B. Tesar, Lisa J. Benincosa et al. · mAbs · 2012 · 135 citations · Full text

Immunocytochemical Technique, Immunology, Pharmacotherapy +17

Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys

Maya K. Leabman, Y. Gloria Meng, Robert F. Kelley et al. · mAbs · 2013 · 107 citations · Full text

Immune Regulation, Immunology, Glycobiology +23

Identification of Shc as the Primary Protein Binding to the Tyrosine-phosphorylated β3 Subunit of αIIbβ3 during Outside-in Integrin Platelet Signaling

Kyra J. Cowan, Debbie A. Law, David R. Phillips · Journal of Biological Chemistry · 2000 · 91 citations · Full text

Polyglutamine protein aggregation and toxicity are linked to the cellular stress response

Kyra J. Cowan · Human Molecular Genetics · 2003 · 78 citations · Full text

Molecular Regulation, Apoptosis, Immunology +21