Leonie K. de Klerk

Gain-of-Function <i>RHOA</i> Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

Haisheng Zhang, Antje Schaefer, Yichen Wang et al. · Cancer Discovery · 2019 · 165 citations · Full text

Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas

Sarah Derks, Leonie K. de Klerk, Xiaoshu Xu et al. · Annals of Oncology · 2020 · 146 citations · Full text

Immune Evasion, Cancer Immunosurveillance, Esophageal Cancer +12

Pre-treatment tumor-infiltrating T cells influence response to neoadjuvant chemoradiotherapy in esophageal adenocarcinoma

Ruben S. A. Goedegebuure, Micaela Harrasser, Leonie K. de Klerk et al. · OncoImmunology · 2021 · 33 citations · Full text

Phase II study of pembrolizumab in refractory esophageal cancer with correlates of response and survival

Leonie K. de Klerk, Anuj Patel, Sarah Derks et al. · Journal for ImmunoTherapy of Cancer · 2021 · 28 citations · Full text

Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies

Leonie K. de Klerk, Ruben S. A. Goedegebuure, Nicole C.T. van Grieken et al. · Molecular Oncology · 2021 · 10 citations · Full text

Esophageal Cancer, Gastrointestinal Oncology, Personalized Treatment Strategies +15