Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

Jonathan J. Keats, Rafaël Fonseca, Marta Chesi, +27

Cancer Cell

Hematological MalignancyMedicineCancer Cell BiologyMultiple MyelomaCancer Genetics +5

Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

Tait D. Shanafelt, Xin V. Wang, Neil E. Kay, +18

New England Journal of Medicine

Clonal competition with alternating dominance in multiple myeloma

Jonathan J. Keats, Marta Chesi, Jan B. Egan, +14

Blood

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, +9

Blood

Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL

Wei Ding, Betsy LaPlant, Timothy G. Call, +32

Blood

Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

Jan B. Egan, Chang-Xin Shi, Waibhav Tembe, +13

Blood

Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma

Oksana Zavidij, Nicholas J. Haradhvala, Tarek H. Mouhieddine, +26

Nature Cancer

Hematological MalignancySingle Cell SequencingMedicineImmunologyPathology +12

Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes

K. Martin Kortüm, K. Elias, Nur Hafzan Md Hanafiah, +16

Blood

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

George Vasmatzis, Sarah H. Johnson, Ryan A. Knudson, +19

Blood

Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas

Esteban Braggio, Scott Van Wier, Juhi Ojha, +14

Clinical Cancer Research