Tasuku Sawa

Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.

Toshiyasu Sasaoka, Manabu Ishiki, Tasuku Sawa et al. · Endocrinology · 1996 · 113 citations · Full text

Insulin Receptors, Insulin Signaling, Systems Biology +15

Two naturally occurring mutations in the kinase domain of insulin receptor accelerate degradation of the insulin receptor and impair the kinase activity.

Teruhiko Imamura, Yasumitsu Takata, Toshiyasu Sasaoka et al. · Journal of Biological Chemistry · 1994 · 42 citations · Full text

Molecular Biology, Insulin Receptor Gene, Insulin Receptor +20

Functional Importance of Amino-terminal Domain of Shc for Interaction with Insulin and Epidermal Growth Factor Receptors in Phosphorylation-independent Manner

Toshiyasu Sasaoka, Hajime Ishihara, Tasuku Sawa et al. · Journal of Biological Chemistry · 1996 · 38 citations · Full text

Hsp70 Family Molecular Chaperones and Mutant Insulin Receptor: Differential Binding Specificities of BiP and Hsp70/Hsc70 Determines Accumulation or Degradation of Insulin Receptor

Tasuku Sawa, Takeshi Imamura, Tetsuro Haruta et al. · Biochemical and Biophysical Research Communications · 1996 · 34 citations

Hsp70/hsc70 Determines Accumulation, Protein Function, Signal Transduction +11

Fatty acid induced insulin resistance in rat-1 fibroblasts overexpressing human insulin receptors: impaired insulin-stimulated mitogen-activated protein kinase activity

Isao Usui, Yasumitsu Takata, Takeshi Imamura et al. · Diabetologia · 1997 · 30 citations · Full text

Insulin Resistance, Metabolic Syndrome, Human Insulin Receptors +13