John R. Engen

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

Wenjun Zhou, Dalia Ercan, Liang Chen et al. · Nature · 2009 · 988 citations · Full text

Egfr T790m, Medicine, Receptor Tyrosine Kinase +3

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

Jianming Zhang, Francisco Adrián, Wolfgang Jahnke et al. · Nature · 2010 · 590 citations

Molecular Pharmacology, Drug Target, Medicine +5

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

Damian J. Houde, Yucai Peng, Steven A. Berkowitz et al. · Molecular & Cellular Proteomics · 2010 · 392 citations · Full text

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

Damian J. Houde, Steven A. Berkowitz, John R. Engen · Journal of Pharmaceutical Sciences · 2010 · 376 citations

Biochemistry, Gas Chromatography, Medicine +10

High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius

Thomas E. Wales, Keith E. Fadgen, Geoff C. Gerhardt et al. · Analytical Chemistry · 2008 · 367 citations