Jianle Wang

Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Jian Chen, Jun-Jun Xie, Mengyun Jin et al. · Cell Death and Disease · 2018 · 135 citations · Full text

Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration

Jianle Wang, Majid Nisar, Chongan Huang et al. · Experimental & Molecular Medicine · 2018 · 93 citations · Full text

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Haiming Jin, Zengjie Zhang, Chengui Wang et al. · Experimental & Molecular Medicine · 2018 · 89 citations · Full text

Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition

Yu Chen, Yanqing Wu, Hongxue Shi et al. · Journal of Cellular and Molecular Medicine · 2019 · 82 citations · Full text

Mitophagy, Apoptosis Inhibition, Apoptosis +21

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration

Daoliang Xu, Haiming Jin, Jianxia Wen et al. · Pharmacological Research · 2017 · 79 citations

Reductive Stress, Mitochondrial Function, Biochemistry +12