Ed C. Lavelle

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

Caroline E. Sutton, Stephen J. Lalor, Cheryl Sweeney et al. · Immunity · 2009 · 1.5K citations · Full text

Life Sciences, Immunology, Pathology +16

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Life Sciences, Endocrinology, Immunology +14

A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis

Caroline E. Sutton, Corinna F. Brereton, Brian Keogh et al. · The Journal of Experimental Medicine · 2006 · 992 citations · Full text

Life Sciences, Immunology, Pathology +17

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

James Harris, Michelle Hartman, Caitrionna Roche et al. · Journal of Biological Chemistry · 2011 · 785 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

Alexander U. Lüthi, Sean P. Cullen, Edel A. McNeela et al. · Immunity · 2009 · 667 citations · Full text

Life Sciences, Cell Biology, Immunology +14