Helen McLaughlin

Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice

Sam Hana, Michael Peterson, Helen McLaughlin et al. · Gene Therapy · 2021 · 43 citations · Full text

Systems Analysis of Transcriptomic and Proteomic Profiles Identifies Novel Regulation of Fibrotic Programs by miRNAs in Pulmonary Fibrosis Fibroblasts

Steven Mullenbrock, Fei Liu, Suzanne Szak et al. · Genes · 2018 · 33 citations · Full text

Engineering, Inflammatory Lung Disease, Lung Inflammation +23

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model

Yi A. Chen, Mark W. Kankel, Sam Hana et al. · Gene Therapy · 2022 · 25 citations · Full text

Vivo Genome, Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis +10

Whole Genome Sequencing Reveals a Chromosome 9p Deletion Causing DOCK8 Deficiency in an Adult Diagnosed with Hyper IgE Syndrome Who Developed Progressive Multifocal Leukoencephalopathy

Aaron Day-Williams, Chao Sun, Ilijas Jelčić et al. · Journal of Clinical Immunology · 2014 · 22 citations · Full text

Genetic mutation analysis at early stages of cell line development using next generation sequencing

Chapman Wright, Joost Groot, Samantha Swahn et al. · Biotechnology Progress · 2016 · 20 citations

Engineering, Genetics, High Throughput +25