Chengxiang Chu

Dual Methylation-Sensitive Restriction Endonucleases Coupling with an RPA-Assisted CRISPR/Cas13a System (DESCS) for Highly Sensitive Analysis of DNA Methylation and Its Application for Point-of-Care Detection

Xianfeng Wang, Shiying Zhou, Chengxiang Chu et al. · ACS Sensors · 2021 · 97 citations

Rpa-assisted Crispr/cas13a System, Engineering, Incomplete Digestion +21

Synthesis of yttrium(III)-based rare-earth metal-organic framework nanoplates and its applications for sensing of fluoride ions and pH

Xianfeng Wang, Chengxiang Chu, Yawen Wu et al. · Sensors and Actuators B Chemical · 2020 · 73 citations

Materials Science, Inorganic Chemistry, Engineering +11

Target-induced transcription amplification to trigger the trans-cleavage activity of CRISPR/Cas13a (TITAC-Cas) for detection of alkaline phosphatase

Xianfeng Wang, Shiying Zhou, Chengxiang Chu et al. · Biosensors and Bioelectronics · 2021 · 36 citations

Off-target Effect, Medicine, Natural Sciences +9

Four-stage signal amplification for trace ATP detection using allosteric probe-conjugated strand displacement and CRISPR/Cpf1 trans-cleavage (ASD-Cpf1)

Xianfeng Wang, Xiaolong Chen, Chengxiang Chu et al. · Sensors and Actuators B Chemical · 2020 · 34 citations

Four-stage Signal Amplification, Biochemistry, Crispr/cpf1 Trans-cleavage +9

Naked-eye detection of site-specific ssRNA and ssDNA using PAMmer-assisted CRISPR/Cas9 coupling with exponential amplification reaction

Xianfeng Wang, Xiaolong Chen, Chengxiang Chu et al. · Talanta · 2021 · 18 citations

Engineering, Medicine, Genetics +14