Leila Khalaj

Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia

Ghorbangol Ashabi, Leila Khalaj, Fariba Khodagholi et al. · Metabolic Brain Disease · 2014 · 247 citations

Inflammation, Metabolic Syndrome, Inhibits Inflammatory Responses +14

Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress

Solaleh Khoramian Tusi, Leila Khalaj, Ghorbangol Ashabi et al. · Biomaterials · 2011 · 205 citations

Mitophagy, Biochemistry, Mitochondrial Function +7

Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: Interference of AMPK/PGC-1α pathway

Ghorbangol Ashabi, Fariba Khodagholi, Leila Khalaj et al. · Metabolic Brain Disease · 2014 · 118 citations

Global Cerebral Ischemia, Cellular Physiology, Social Sciences +16

Metformin pretreatment enhanced learning and memory in cerebral forebrain ischaemia: the role of the AMPK/BDNF/P70SK signalling pathway

Negar Ghadernezhad, Leila Khalaj, Hamidreza Pazoki–Toroudi et al. · Pharmaceutical Biology · 2016 · 80 citations · Full text

Brain Function, Social Sciences, Cerebral Vascular Regulation +23

Metformin improves anxiety-like behaviors through AMPK-dependent regulation of autophagy following transient forebrain ischemia

Alireza Sarkaki, Yaghoob Farbood, Mohammad Badavi et al. · Metabolic Brain Disease · 2015 · 77 citations