Christian W. Siebel

Therapeutic antibody targeting of individual Notch receptors

Yan Wu, Carol Cain-Hom, Lisa Choy et al. · Nature · 2010 · 710 citations · Full text

Immunology, Receptor (Biochemistry), Immunochemistry +5

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

Kelli L. VanDussen, Alexis J. Carulli, Theresa M. Keeley et al. · Development · 2011 · 552 citations

Adult Stem Cell, Immunology, Immune Regulation +21

Notch signalling drives synovial fibroblast identity and arthritis pathology

Kevin Wei, Ilya Korsunsky, Jennifer L. Marshall et al. · Nature · 2020 · 494 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +10

Endothelial Notch1 Activity Facilitates Metastasis

Elfriede Wieland, Juan Rodríguez‐Vita, Sven S. Liebler et al. · Cancer Cell · 2017 · 310 citations · Full text

Endothelial Cell Pathobiology, Angiogenesis, Endothelial Dysfunction +5

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

Daniel Lafkas, Amy L. Shelton, Cecilia Chiu et al. · Nature · 2015 · 238 citations

Notch Control, Inflammatory Lung Disease, Lung Inflammation +13