Ann Smith

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

John D. Belcher, Chunsheng Chen, Julia Nguyen et al. · Blood · 2013 · 671 citations · Full text

A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

Rasmus Larsen, Raffaella Gozzelino, Viktória Jeney et al. · Science Translational Medicine · 2010 · 481 citations · Full text

Heme Oxygenase-1 Protein Localizes to the Nucleus and Activates Transcription Factors Important in Oxidative Stress

Qing Lin, Sebastian Weis, Guang Yang et al. · Journal of Biological Chemistry · 2007 · 419 citations · Full text

Molecular Biology, Redox Biology, Cellular Physiology +17

Antioxidant protection by haemopexin of haem-stimulated lipid peroxidation

John M.C. Gutteridge, Ann Smith · Biochemical Journal · 1988 · 282 citations · Full text

Inflammation, Oxygen-radical Reactions, Biochemistry +14

Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two beta-propeller domains.

Edward N. Baker, Massimo De Paoli, Bryan F. Anderson et al. · Nature Structural Biology · 1999 · 237 citations

Crystal Structure, Biochemistry, Heme Homeostasis +9