Elizabeth J. Osterlund

Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2

Qian Liu, Elizabeth J. Osterlund, Xiaoke Chi et al. · eLife · 2019 · 62 citations · Full text

Apoptosis, Cell Death, Pharmacotherapy +19

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

Xiaoke Chi, Dang Nguyen, James M. Pemberton et al. · eLife · 2020 · 45 citations · Full text

Mitophagy, Apoptosis, Cell Death +17

Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells

Elizabeth J. Osterlund, Nehad Hirmiz, James M. Pemberton et al. · Science Advances · 2022 · 29 citations · Full text

Drug Target, Chemoprevention Strategy, Apoptosis +20

The Use of FLIM-FRET for the Detection of Mitochondria-Associated Protein Interactions

Elizabeth J. Osterlund, Qian Liu, David W. Andrews · Methods in molecular biology · 2015 · 22 citations

Mitochondrial Function, Biochemistry, Protein Folding +7

Highly Multiplexed Confocal Fluorescence Lifetime Microscope Designed for Screening Applications

Nehad Hirmiz, Anthony Tsikouras, Elizabeth J. Osterlund et al. · IEEE Journal of Selected Topics in Quantum Electronics · 2020 · 17 citations

Engineering, Microscopy, Molecular Biology +21