DNA hypermethylation during tuberculosis dampens host immune responsiveness

Andrew R. DiNardo, Kimal Rajapakshe, Tomoki Nishiguchi, +14

Journal of Clinical Investigation

Clinical ImmunologyImmunodeficienciesImmunologyImmune RegulationInnate Immunity +17

Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes

Andrew R. DiNardo, Tomoki Nishiguchi, Emily M. Mace, +12

The Journal of Immunology

M2b Monocytes Provoke Bacterial Pneumonia and Gut Bacteria–Associated Sepsis in Alcoholics

Yusuke Tsuchimoto, Akira Asai, Yasuhiro Tsuda, +7

The Journal of Immunology

DysbiosisMicrobial PathogensInnate Immune SystemImmunologyImmune Regulation +25

Tuberculosis endotypes to guide stratified host-directed therapy

Andrew R. DiNardo, Tomoki Nishiguchi, Sandra L. Grimm, +10

Med

Pulmonary TuberculosisTuberculosis PreventionImmunologyTuberculosisTuberculosis Endotypes +4

Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis

Carly A. Bobak, Abhimanyu Abhimanyu, Harini Natarajan, +13

Aging

Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes

Andrew R. DiNardo, Tanmay Gandhi, Jan Heyckendorf, +10

European Respiratory Journal

Protective effect of porphyran isolated from discolored nori (Porphyra yezoensis) on lipopolysaccharide-induced endotoxin shock in mice

Tomoki Nishiguchi, Kichul Cho, Shogo Isaka, +5

International Journal of Biological Macromolecules

Microbial ToxinMedicineLipopolysaccharide-induced Endotoxin ShockToxicologyMicrobiology +7

Inhibitory effect of sulphated polysaccharide porphyran (isolated from <i><scp>Porphyra yezoensis</scp>)</i> on <scp>RANKL</scp>‐induced differentiation of <scp>RAW264.7</scp> cells into osteoclasts

M. Ueno, Kichul Cho, Shogo Isaka, +4

Phytotherapy Research

Importance of sulfate groups for the macrophage-stimulating activities of ascophyllan isolated from the brown alga Ascophyllum nodosum

Zedong Jiang, M. Ueno, Tomoki Nishiguchi, +5

Carbohydrate Research

BiologyEngineeringMacrophage-stimulating ActivitiesOomyceteMicrobiology +4

Macrophage polarization and MRSA infection in burned mice

Tomoki Nishiguchi, Ichiaki Ito, Jong O. Lee, +3

Immunology and Cell Biology