Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction

Yuan Qiao, Matthew D. Lebar, Kathrin Schirner, +4

Journal of the American Chemical Society

Proteinlipid InteractionLipid IiProtein AssemblyGlycobiologyMolecular Biology +14

Lipid II overproduction allows direct assay of transpeptidase inhibition by β-lactams

Yuan Qiao, Veerasak Srisuknimit, Frederick A. Rubino, +4

Nature Chemical Biology

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

Zhenxing Huang, Jianhe Wang, Xiaoli Xu, +16

Nature Microbiology

InflammationAllergyAutoimmune DiseaseHumoral ResponseImmunology +7

A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection

Chew Teng Tan, Xiaoli Xu, Yuan Qiao, +1

Nature Communications

In vitro reconstitution demonstrates the cell wall ligase activity of LCP proteins

Kaitlin Schaefer, Leigh M. Matano, Yuan Qiao, +2

Nature Chemical Biology

Protein FunctionProtein ExpressionVitro ReconstitutionCell RegulationNatural Sciences +7

Color-related chlorophyll and carotenoid concentrations of Chinese kale can be altered through CRISPR/Cas9 targeted editing of the carotenoid isomerase gene BoaCRTISO

Bo Sun, Min Jiang, Hao Zheng, +12

Horticulture Research

Variation in the main health-promoting compounds and antioxidant activity of whole and individual edible parts of baby mustard (<i>Brassica juncea</i> var. <i>gemmifera</i>)

Bo Sun, Yuxiao Tian, Min Jiang, +6

RSC Advances

Peptidoglycan Cross-Linking Preferences of <i>Staphylococcus aureus</i> Penicillin-Binding Proteins Have Implications for Treating MRSA Infections

Veerasak Srisuknimit, Yuan Qiao, Kaitlin Schaefer, +2

Journal of the American Chemical Society

Microbial PathogensGlycobiologyBacteriologyDifferent Glycine BranchesTreating Mrsa Infections +16

The Mechanism of Action of Lysobactin

Wonsik Lee, Kaitlin Schaefer, Yuan Qiao, +5

Journal of the American Chemical Society

Inhibitory ActivityMolecular PhysiologySignal TransductionBiochemistryLipid Ii +12

Apigenin Alleviates Obesity-Associated Metabolic Syndrome by Regulating the Composition of the Gut Microbiome

Yuan Qiao, Zhichun Zhang, Yuanyuan Zhai, +5

Frontiers in Microbiology