Monoclonal antibody-mediated enhancement of dengue virus infection<i>in vitro</i>and<i>in vivo</i>and strategies for prevention

Ana P. Goncalvez, Ronald E. Engle, Marisa St. Claire, +2

Proceedings of the National Academy of Sciences

Dengue VirusImmunologyViral PathogenesisViral Structural ProteinImmunotherapy +14

Diversity and Evolution of the Envelope Gene of Dengue Virus Type 1

Ana P. Goncalvez, Ananías A. Escalante, Flor H. Pujol, +4

Virology

Viral EvolutionGeneticsPathogenesisEvolutionary BiologyEnvelope Gene +8

Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus

J.J.B. Cockburn, M.E. Navarro Sanchez, Ana P. Goncalvez, +8

The EMBO Journal

VaccinationVirus StructureStructural InsightsNeutralization MechanismImmunology +7

Epitope Determinants of a Chimpanzee Fab Antibody That Efficiently Cross-Neutralizes Dengue Type 1 and Type 2 Viruses Map to Inside and in Close Proximity to Fusion Loop of the Dengue Type 2 Virus Envelope Glycoprotein

Ana P. Goncalvez, Robert H. Purcell, Ching‐Juh Lai

Journal of Virology

ImmunologyViral PathogenesisMolecular BiologyNovel EpitopeViral Structural Protein +14

Epitope Determinants of a Chimpanzee Dengue Virus Type 4 (DENV-4)-Neutralizing Antibody and Protection against DENV-4 Challenge in Mice and Rhesus Monkeys by Passively Transferred Humanized Antibody

Ching‐Juh Lai, Ana P. Goncalvez, Ruhe Men, +4

Journal of Virology

ImmunologyViral PathogenesisViral Structural ProteinImmunotherapyRhesus Monkeys +15

Humanized Monoclonal Antibodies Derived from Chimpanzee Fabs Protect against Japanese Encephalitis Virus In Vitro and In Vivo

Ana P. Goncalvez, Cheng-Hsin Chien, Kamolchanok Tubthong, +8

Journal of Virology

Viral PathogenesisImmunologyViral Structural ProteinImmunotherapyFab B2 +14

Dengue virus neutralization is modulated by IgG antibody subclass and Fcγ receptor subtype

W. W. Shanaka I. Rodrigo, Olivia K.T. Block, Christopher Lane, +8

Virology

Viral PathogenesisImmunologyImmunodominanceVirologyAntiviral Response +8

Identification of Chimpanzee Fab Fragments by Repertoire Cloning and Production of a Full-Length Humanized Immunoglobulin G1 Antibody That Is Highly Efficient for Neutralization of Dengue Type 4 Virus

Ruhe Men, Tetsu Yamashiro, Ana P. Goncalvez, +5

Journal of Virology

Chimeric yellow fever 17D-Zika virus (ChimeriVax-Zika) as a live-attenuated Zika virus vaccine

Maryann Giel–Moloney, Ana P. Goncalvez, John Catalan, +11

Scientific Reports

Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses

Ana P. Goncalvez, Ruhe Men, Claire Wernly, +2

Journal of Virology