A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

Ferry Ossendorp, Maren Eggers, Anne Neisig, +8

Immunity

Viral ReplicationProtein FunctionProtein FoldingMedicineNatural Sciences +11

Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing

Anne Neisig, Richard Wubbolts, Xuege Zang, +2

The Journal of Immunology

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences.

Anne Neisig, J Roelse, Alice J.A.M. Sijts, +5

The Journal of Immunology

HistocompatibilityMajor DifferencesImmunogeneticsSignal TransductionMhc Class +13

Induction of Lectin-like Transcript 1 (LLT1) Protein Cell Surface Expression by Pathogens and Interferon-γ Contributes to Modulate Immune Responses

Claire Germain, Anders Meier, Teis Jensen, +10

Journal of Biological Chemistry

Adaptive Immune SystemInnate Immune SystemImmune RegulationImmunologyImmunologic Mechanism +20

Point mutations in the α2 domain of HLA-A2.1 define a functionally relevant interaction with TAP

Jonathan W. Lewis, Anne Neisig, Jacques Neefjes, +1

Current Biology

Histocompatibilityα2 DomainSignal TransductionPoint MutationsProtein Function +7

Reduced Cell Surface Expression of HLA-C Molecules Correlates with Restricted Peptide Binding and Stable TAP Interaction

Anne Neisig, Cornelis J.M. Melief, Jacques Neefjes

The Journal of Immunology

Protein SecretionCell AdhesionHla ImmunogeneticsImmunologyMolecular Biology +18

Phosphorylated Peptides Can Be Transported by TAP Molecules, Presented by Class I MHC Molecules, and Recognized by Phosphopeptide-Specific CTL

Mads Hald Andersen, Jordi Espuny Bonfill, Anne Neisig, +6

The Journal of Immunology

ImmunologyMolecular BiologyAntigen ProcessingMhc MoleculesTap Transport +14

Presentation of Cytosolic Glycosylated Peptides by Human Class I Major Histocompatibility Complex Molecules in Vivo

John S. Haurum, Ingelise Bjerring Høier, Gemma Arsequell, +5

The Journal of Experimental Medicine

Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies

Alice J.A.M. Sijts, Anne Neisig, Jacques Neefjes, +1

The Journal of Immunology

Abrogation of CTL Epitope Processing by Single Amino Acid Substitution Flanking the C-Terminal Proteasome Cleavage Site

N. J. C. M. Beekman, Peter A. van Veelen, Thorbald van Hall, +7

The Journal of Immunology

Protein AssemblyImmunologyProteasomeMolecular BiologyAntigen Processing +17