Xavier Altafaj - Concepedia

Author

Xavier Altafaj

Universitat de Barcelona ORCID

Also Known As

Altafaj, Xavier, X Altafaj, X. Altafaj, Xavier Altafaj

Publications

Citations

H-Index

Concepts

All Affiliations

Universitat de Barcelona Institut d'Investigació Biomédica de Bellvitge Centre for Biomedical Network Research on Rare Diseases Inserm Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

About

Xavier Altafaj is an author at Universitat de Barcelona specializing in medicine, cell biology, and molecular neuroscience.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	14	15	768
2	Social Sciences	7	7	405
3	Engineering	3	3	100
4	Natural Sciences	2	2	98
5	Health Sciences	1	1	15

Xavier Altafaj

Publications

1.8K

Citations

H-Index

Page 1

	Year	Citations
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome Xavier Altafaj Human Molecular Genetics	2001	392
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system Eulàlia Martı́, Xavier Altafaj, Mara Dierssen, Brain Research Signal TransductionMolecular NeuroscienceSignaling PathwayCell SignalingMedicine	2003	134
Interaction between the dihydropyridine receptor Ca <sup>2+</sup> channel β-subunit and ryanodine receptor type 1 strengthens excitation-contraction coupling Weijun Cheng, Xavier Altafaj, Michel Ronjat, Proceedings of the National Academy of Sciences	2005	90
DYRK1A Autophosphorylation on Serine Residue 520 Modulates Its Kinase Activity via 14-3-3 Binding Mónica Álvarez‐Fernández, Xavier Altafaj, Sergi Aranda, Molecular Biology of the Cell GeneticsMolecular BiologySignaling PathwayCell RegulationReceptor Tyrosine Kinase	2007	85
Cloning and Characterization of DYRK1B, a Novel Member of the DYRK Family of Protein Kinases Susanne Leder, Yvonne Weber, Xavier Altafaj, Biochemical and Biophysical Research Communications Signal TransductionDyrk FamilyReceptor Tyrosine KinaseProtein KinasesMolecular Biology	1999	82
<scp>l</scp> -Serine dietary supplementation is associated with clinical improvement of loss-of-function <i>GRIN2B</i> -related pediatric encephalopathy David Soto, Mireia Olivella, C. J. Alejos Grau, Science Signaling	2019	82
Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction María Martínez de Lagrán, Xavier Altafaj, Xavier Gallego, Neurobiology of Disease Down SyndromeKnockout MouseNeurodegenerative DiseasesMolecular NeuroscienceDevelopmental Biology	2003	76
Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome Xavier Altafaj, E. Martin, Jon Ortiz-Abalia, Neurobiology of Disease Down SyndromeNeurodegenerative DiseasesSignal TransductionMolecular NeuroscienceTs65dn Mouse Model	2012	76
Targeting Dyrk1A with AAVshRNA Attenuates Motor Alterations in TgDyrk1A, a Mouse Model of Down Syndrome Jon Ortiz-Abalia, Ignasi Sahún, Xavier Altafaj, The American Journal of Human Genetics Down SyndromeKnockout MouseDevelopmental BiologyMolecular NeuroscienceSignal Transduction	2008	68
Transduction of the Scorpion Toxin Maurocalcine into Cells É. Estève, Kamel Mabrouk, Alain Dupuis, Journal of Biological Chemistry	2005	68

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