Concepedia

Mark M. Hisaka

MM

8

Publications

990

Citations

8

H-Index

1992

Active since

Affiliations

University of North Carolina at Chapel Hill(Current)

Sanford Burnham Prebys Medical Discovery Institute

Discovery Institute

National Foundation for Cancer Research

Mark M. Hisaka is an author at University of North Carolina at Chapel Hill specializing in cell signaling, signal transduction, and cell biology.

Top concepts

Publications per year

1992–1996

8

Publications

8

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.

Kiyoko Kato, Adrienne D. Cox, Mark M. Hisaka et al. · Proceedings of the National Academy of Sciences · 1992 · 541 citations

, , +20

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.

Adrienne D. Cox, Mark M. Hisaka, Janice E. Buss et al. · Molecular and Cellular Biology · 1992 · 180 citations

, , +17

Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors.

L A Quilliam, Kiyoko Kato, K M Rabun et al. · Molecular and Cellular Biology · 1994 · 90 citations · Full text

, , +16

Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein.

Geoffrey Clark, Lawrence A. Quilliam, Mark M. Hisaka et al. · Proceedings of the National Academy of Sciences · 1993 · 57 citations · Full text

, , +18

Involvement of the Switch 2 Domain of Ras in Its Interaction with Guanine Nucleotide Exchange Factors

Lawrence A. Quilliam, Mark M. Hisaka, Sheng Zhong et al. · Journal of Biological Chemistry · 1996 · 52 citations · Full text

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