Daniel E. Jeffries

Discovery of VU6015929: A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy

Daniel E. Jeffries, Corina M. Borza, Anna L. Blobaum et al. · ACS Medicinal Chemistry Letters · 2019 · 28 citations · Full text

Antifibrotic Therapy, Good Kinome Selectivity, Novel Therapy +12

Synthesis and characterization of a series of chiral alkoxymethyl morpholine analogs as dopamine receptor 4 (D4R) antagonists

Jonathan O. Witt, Andrea L. McCollum, Miguel Hurtado et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 26 citations · Full text

Combinatorial Chemistry, Molecular Pharmacology, Medicinal Chemistry +9

Discovery, characterization and biological evaluation of a novel (R)-4,4-difluoropiperidine scaffold as dopamine receptor 4 (D4R) antagonists

Daniel E. Jeffries, Jonathan O. Witt, Andrea L. McCollum et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 17 citations

Potent Uncompetitive Inhibitors of Nicotinamide <i>N</i>-Methyltransferase (NNMT) as In Vivo Chemical Probes

Robert D. Barrows, Daniel E. Jeffries, Mahesh Vishe et al. · Journal of Medicinal Chemistry · 2022 · 16 citations · Full text