Xiangyang Le

Discovery of a Dual Tubulin Polymerization and Cell Division Cycle 20 Homologue Inhibitor via Structural Modification on Apcin

Pan Huang, Xiangyang Le, Fei Huang et al. · Journal of Medicinal Chemistry · 2020 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Explore drug-like space with deep generative models

Jianmin Wang, Yunyun Wang, Xiangyang Le et al. · Methods · 2023 · 31 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +5

Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model

Congke Zhao, Xiangyang Le, Mengqi Li et al. · Respiratory Research · 2023 · 23 citations · Full text

Medicine, Molecular Biology, Pharmacology +15