Murray L. Whitelaw

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

David Lando, Daniel J. Peet, Dean A. Whelan et al. · Science · 2002 · 1.5K citations

Chemical Biology, Reductive Stress, Transcriptional Regulation +15

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

David Lando, Daniel J. Peet, Jeffrey J. Gorman et al. · Genes & Development · 2002 · 1.5K citations · Full text

Functional Interference between Hypoxia and Dioxin Signal Transduction Pathways: Competition for Recruitment of the Arnt Transcription Factor

Katarina Gradin, Jacqueline McGuire, Roland H. Wenger et al. · Molecular and Cellular Biology · 1996 · 470 citations · Full text

Molecular Biology, Redox Biology, Oxidative Stress +17

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

Patrik Andersson, Jacqueline McGuire, Carlos Rubio-Terrés et al. · Proceedings of the National Academy of Sciences · 2002 · 302 citations · Full text

Gastrointestinal Peptide Hormone, Biochemistry, Gastrointestinal Oncology +13

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

Xiaofeng Zheng, Sarah Linke, José M. Dias et al. · Proceedings of the National Academy of Sciences · 2008 · 268 citations · Full text

Hif-1 Defines, Additional Mode, Notch Icd +20